Satb1 regulates the effector program of encephalitogenic tissue Th17 cells in chronic inflammation

Keiko Yasuda (Osaka University Hospital/Graduate School of Medicine), Keiji Hirota, Shimon Sakaguchi (Experimental Immunology, IFReC) and their research group demonstrate that Satb1 differentially regulates gene expression profiles in non-pathogenic and pathogenic Th17 cells and promotes the pathogenic effector program of encephalitogenic Th17 cells.

Commentary (PDF)

Article (External Link)