Yoshiaki Yasumizu, Naganari Ohkura (Graduate School of Medicine, Osaka University), and Shimon Sakaguchi (Experimental Immunology, IFReC) and their group compile a comprehensive reference of circulating CD4+ T cells, encompassing 12 gene programs and 18 clusters. They reveal disease-specific cellular characteristics through the integration of genome-wide association studies and single-cell meta-analysis. This work provides insights for precision medicine.
(online publishing in Cell Genomics on January 4, 2024)
Single-cell transcriptome landscape of circulating CD4+ T cell populations in autoimmune diseases
January 05, 2024
