How myasthenia gravis develops in thymoma patients? (Ohkura & Sakaguchi G, in Nat Commun.)

Although Myasthenia gravis (MG) frequently develops in thymoma patients, the etiologic factors for MG are not well understood. By constructing a comprehensive atlas of thymoma using bulk and single-cell RNA-sequencing, Naganari Ohkura (IFReC/Graduate School of Medicine, Osaka University, Shimon Sakaguchi (Experimental Immunology, IFReC) identified ectopic expression of neuromuscular molecules in MG-type thymoma.


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