Shimon SAKAGUCHI won the Gairdner International Award
March 25, 2015
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The Gairdner Foundation announced on March 25 that Prof Shimon Sakaguchi and the six other scientists are awar […]
Continue Reading →Regulatory T cells control antigen-specific expansion of Tfh cell number and humoral immune responses via the coreceptor CTLA-4 (in Immunity)
December 19, 2014
The authors found Treg cells directly inhibited, via CTLA-4, B cell expression of CD80 and CD86, which was ess […]
Continue Reading →Detection of self-reactive CD8+ T cells with an anergic phenotype in healthy individuals (in Science)
December 19, 2014
The authors found Treg can render self-reactive human CD8+ T cells anergic (i.e., hypoproliferative and cytoki […]
Continue Reading →Detection of T cell responses to a ubiquitous cellular protein in autoimmune disease (in Science)
October 17, 2014
Tcells that mediate autoimmune diseases such as rheumatoid arthritis (RA) are difficult to characterize becaus […]
Continue Reading →”Differential roles of epigenetic changes and Foxp3 expression in regulatory T cell-specific transcriptional regulation (PNAS)” was published
March 27, 2014
Differential roles of epigenetic changes and Foxp3 expression in regulatory T cell-specific transcripti […]
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