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Two FOXP3+CD4+ T-cell subpopulations distinctly control the prognosis of colorectal cancers (Sakaguchi group, in Nat Med)

April 26, 2016
by ssakaguchi
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Shimon Sakaguchi’s group (Experimental Immunology) and others revealed that Colorectal cancers (CRCs), w […]
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Immuno-Navigator, a batch-corrected coexpression database, reveals cell type-specific gene networks in the immune system

April 15, 2016
by ssakaguchi
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An IFReC interdisciplinary project was conducted by a group including Alexis Vandenbon (Immuno-Genomics Unit) […]
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Shimon Sakaguchi awarded “Suita City Mayor’s Prize”

November 25, 2015
by ssakaguchi
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“Suita City Mayor’s Prize” was awarded to Professor Shimon Sakaguchi (Deputy Director, Exper […]
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Shimon SAKAGUCHI elected Thomson Reuters Citation Laureates

October 07, 2015
by ssakaguchi
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Shimon Sakaguchi (Experimental Immunology, IFReC) was elected the Thomson Reuters Citation Laureate 2015. The […]
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Shimon Sakaguchi won the Chunichi award

May 25, 2015
by ssakaguchi
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Prof. Shimon Sakaguchi won the 68th Chunichi Award, and the award ceremony was held on May 25. The Chunichi aw […]
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Shimon SAKAGUCHI won the Gairdner International Award

March 25, 2015
by ssakaguchi
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The Gairdner Foundation announced on March 25 that Prof Shimon Sakaguchi and the six other scientists are awar […]
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Regulatory T cells control antigen-specific expansion of Tfh cell number and humoral immune responses via the coreceptor CTLA-4 (in Immunity)

December 19, 2014
by ssakaguchi
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The authors found Treg cells directly inhibited, via CTLA-4, B cell expression of CD80 and CD86, which was ess […]
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Detection of self-reactive CD8+ T cells with an anergic phenotype in healthy individuals (in Science)

December 19, 2014
by ssakaguchi
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The authors found Treg can render self-reactive human CD8+ T cells anergic (i.e., hypoproliferative and cytoki […]
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Detection of T cell responses to a ubiquitous cellular protein in autoimmune disease (in Science)

October 17, 2014
by ssakaguchi
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Tcells that mediate autoimmune diseases such as rheumatoid arthritis (RA) are difficult to characterize becaus […]
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